RAS BiologyПрикладная биохимия и микробиология Applied Biochemistry and Microbiology

  • ISSN (Print) 0555-1099
  • ISSN (Online) 3034-574X

The Methods of Antibacterial Activity Investigation and Mechanism of Antimicrobial Action of Drug Molecules Encapsulated in Delivery Systems

PII
S3034574XS0555109925020013-1
DOI
10.7868/S3034574X25020013
Publication type
Review
Status
Published
Authors
Volume/ Edition
Volume 61 / Issue number 2
Pages
109-127
Abstract
Due to the diversity of the structure and supramolecular architecture of existing antibacterial drug delivery systems, the question of choosing methods for in vitro properties research of the proposed drug forms (DF) and determining the effect of the carrier on the antimicrobial properties of the drug in the research laboratory is especially relevant. The review examines the main microbiological methods of antimicrobial activity investigation that are used in the study of DF, and provides recommendations for choosing a research method in accordance with the type and chemical nature of drug carrier. In addition, instrumental methods and experimental techniques for studying the mechanism of antimicrobial action of DF, as well as in vitro effects, which are most often observed in the literature when the drug is encapsulated in a carrier, are discussed. This review provides the researcher with a strategy for analyzing the antimicrobial properties of the DF based on the system’s physicochemical properties that allows a more comprehensive assessment of the future prospects of drugs.
Keywords
антибактериальная активность системы доставки лекарств микроскопия клеток
Date of publication
10.11.2024
Year of publication
2024
Number of purchasers
0
Views
29

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